Erectile dysfunction or impotence is a condition that becomes more prevalent with increasing age, as demonstrated by the fact that it occurs in approximately 1% of men between 21 and 30 years of age and 47% in those who are 43 years of age or older. There are several potential causes, and some of the more common include disorders such as diabetes, peripheral neuropathy and cardiovascular disease.
However, it can also occur as a side effect of anti-hypertensive medications used to treat high blood pressure. In the PPOD syndrome patient erectile dysfunction is caused by impairment of the neurologic reflexes that normally lead to engorgement of the erectile tissues in the penis. As a result, even with intense arousal and physical stimulation the penis remains flaccid and is incapable of becoming sufficiently firm to engage in intercourse.
One of the features of PPOD syndrome related erectile dysfunction is that in most cases (there are exceptions) there will usually be an accompanying loss of sensory perception to touch or contact over regions of the penis. This loss of sensory perception indicates sensory nerve impairment and is one of the factors involved in disturbing the normal reflex activity associated with penile engorgement. Refer to cases 5 and 13 for examples of the response of impotence to PPOD syndrome treatment.